When two bus crash survivors awake to discover that they are the only people left in their small town, they must form an unlikely alliance in a race to unravel the truth behind their isolation. As strange events begin to unfold, they start to question whether the town they know so well is really what it seems.

Detective John Prudhomme, a Cajun transplanted to Chicago, is assigned to investigate the savage murder of a man who has bled to death from a severed arm. A message, "He Is Coming", written in blood on the victim's window is a dark, forboding clue of his task. After two more victims with missing body parts are discovered, Prudhomme realizes he is on the trail of a serial killer who is using the missing body parts to reconstruct the body of Christ...just in time for Easter. As Prudhomme struggles to catch the zealot-murderer, he is haunted by the death of his son, his continued estrangement from his wife, and his wavering faith in God.

David Leary was bullied by Rosco when he was in elementary school. But he got even on the day his parents moved out of town. Now twenty years later, David, who is a successful writer, is invited back to his home town to teach. Everything is great until Rosco, who is still in town, recognizes him. Now suddenly someone is playing mean practical jokes on him. Isn't David a little too old to be running to the Principal saying "Rosco's picking on me." ?

A group of three criminals on the run from the law, go about terrorizing the local townsfolk of a small community, before descending on an isolated farm which is home to a young girl named Lisa and her paralyzed grandfather. After being sexually assaulted by two of the gangsters, she retaliates using an axe and a razor blade.