Since he was a child, Bart Tare has always loved guns. After leaving the army, his friends take him to a carnival, where he meets the perfect girl; Annie, a sharp-shooting sideshow performer who loves guns as much as he. The 2 run off and marry, but Annie isn't happy with their financial situation, so at her behest the couple begins a cross-country string of daring robberies. Never one to use guns for killing, Bart's dragged down into oblivion by the greedy and violent nature of the woman he loves.

The difficult 1930s is a time of robbers who knock over banks and other rich targets with alarming frequency. Of them, none is more notorious than John Dillinger, whose gang plies its trade with cunning efficiency against big businesses while leaving ordinary citizens alone. As Dillinger becomes a folk hero, FBI head J. Edger Hoover is determined to stop his ilk by assigning ace agent Melvin Purvis to hunt down Dillinger. As Purvis struggles with the manhunt's realities, Dillinger himself faces an ominous future with the loss of friends, dwindling options and a changing world of organized crime with no room for him.

Two bawdy, tough looking navy lifers - "Bad-Ass" Buddusky, and "Mule" Mulhall - are commissioned to escort a young pilferer named Meadows to the brig in Portsmouth. Meadows is not much of a thief. Indeed, in his late teens, he is not much of a man at all. His great crime was to try to steal forty dollars from the admiral's wife's pet charity. For this, he's been sentenced to eight years behind bars. At first, Buddusky and Mulhall view the journey as a paid vacation, but their holiday spirits are quickly depressed by the prisoner, who looks prepared to break into tears at any moment. And he has the lowest self-image imaginable. Buddusky gets it into his head to give Meadows a good time and teach him a bit about getting on in the world. Lesson one: Don't take every card life deals you. Next, he teaches Meadows to drink, and, as a coup de grace, finds a nice young whore to instruct him in lovemaking. Mule, who worries aloud about his own position with military authority, seems pleased ...

Peter Fonda plays 'Heavenly Blues', the leader of the Angels, a motorcycle gang from San Pedro, California; Bruce Dern plays 'Loser', his best pal. When they both botch their attempt to retrieve Loser's stolen bike, Loser ends up in the hospital. When the Angels bust him out, he dies, and they bury him. Nancy Sinatra plays Mike, Blues' "old lady" and Diane Ladd plays Loser's wife (Dern's real-life wife at the time). The plot is basically a buildup to the last half-hour of the film in which Loser's funeral becomes another wild party.