A serial killer known as "The Avenger" is on the loose in London, murdering blonde women. A mysterious man arrives at the house of Mr. and Mrs. Bunting looking for a room to rent. The Bunting's daughter is a blonde model and is seeing one of the detectives assigned to the case. The detective becomes jealous of the lodger and begins to suspect he may be the avenger.

In California, the Caucasian Chris Mattson and his African-American wife Lisa Mattson move to a house in a gated community. The racist and dysfunctional next-door neighbor is the abusive LAPD Officer Abel Turner who feels uncomfortable with the relationship of the newcomers and transforms their lives into Hell on Earth.

It is the early 60s in France. The remaining survivors of the aborted French Foreign Legion have made repeated attempts to kill DeGaulle. The result is that he is the most closely guarded man in the world. As a desperate act, they hire The Jackal, the code name for a hired killer who agrees to kill French President De Gaulle for half a million dollars. We watch his preparations which are so thorough we wonder how he could possibly fail even as we watch the French police attempt to pick up his trail. The situation is historically accurate. There were many such attempts and the film closely follows the plot of the book.

Evelyn Salt is a CIA agent and highly respected by all, including her boss, Ted Winter. Out of the blue, a Russian spy walks into their offices and offers a vital piece of information: the President of Russia will be assassinated during his forthcoming visit to New York City to attend the funeral of the recently deceased U.S. Vice President. The name of the assassin: Evelyn Salt. Concerned about the safety of her husband, who she cannot contact, she goes on the run. Winter refuses to accept that she is a mole or a double agent but her actions begin to raise doubts. Just who is Evelyn Salt and what is she planning?