Two years ago, a young woman named Valerie was burned after entering a tanning salon. Now, her twin sister, Rhonda, runs a local gym where, all of a sudden, people are being murdered.

Smith, a mob informer hiding out with the Witness Protection Program, decides to make a break for it and hide out in the Arizona desert. The Feds catch up with him and rescue him just before a group of hitmen can manage to silence him for good. In the course of getting Smith away from the mafia thugs, the pair of agents assigned to protect him turn onto an abandoned stretch of highway nicknamed 'Route 666' after the mysterious death of a prison chain gang. As the three continue on their way, they soon discover just what happened to the chain gang, and how the highway earned its name.

When European Egyptologists Dubois, Giles and Bray discover the tomb of the Egyptian prince Ra, American entrepreneur and investor Alexander King insists on shipping the treasures and sarcophagus back to England for tour and display. Once there, someone with murderous intent has discovered the means of waking the centuries dead prince...

In August, 1939, a worker goes into labor while working in a slaughterhouse and dies after a complicated labor, though the deformed child survives. The possibly orphaned baby is dumped in a garbage container and found by a beggar later, who brings him home. Along the years, the mentally retarded and disturbed boy called Thomas is raised by the Hewitt family in spite of having psychological problems as well as suffering from an unnamed skin disorder, later working in a meat packing plant. In July, 1969, when the facility is closed, the inhabitants move to other places, but the deformed, mentally childlike Thomas flies into a rage after being insulted and kills the foreman. His deranged brother (considered his uncle due to their age difference) executes the sheriff that is going to arrest Thomas, and assumes his identity, wearing his clothes,driving his car though the roads in Texas and entitling himself as Sheriff Hoyt. Meanwhile, the brothers Eric and Dean are traveling in a Jeep with...