In the year 1971, San Francisco faces the terror of a maniac known as Scorpio- who snipes at innocent victims and demands ransom through notes left at the scene of the crime. Inspector Harry Callahan (known as Dirty Harry by his peers through his reputation handling of homicidal cases) is assigned to the case along with his newest partner Inspector Chico Gonzalez to track down Scorpio and stop him. Using humiliation and cat and mouse type of games against Callahan, Scorpio is put to the test with the cop with a dirty attitude.

While investigating a call in an abandoned house, Officer Frank Williams and a rookie find a woman brutally blinded, but they are attacked by a huge psychopath with an ax; the rookie is killed and Frank shoots the criminal in the head, but has a severed arm. Four years later, the mutilated Frank is relocated, working as a guard in the County Detention Center. Frank goes with some delinquents to the Blackwell Hotel, an abandoned place since a fire burnt the last two floors, with the purpose of cleaning the location, preparing it to work as a shelter for the homeless; in return, the criminals will have their sentences reduced. During the night, the inmate Kira who has some Christian tattoos on her body is kidnapped by the deranged serial-killer Kane who collects the eyes of his victims, while the rest of the group is attacked by the psychopath with his ax.

David Byrne walks onto the stage and does a solo "Psycho Killer." Jerry Harrison, Tina Weymouth and Chris Frantz join him for two more songs. The crew is busy, still setting up. Then, three more musicians and two back-up singers join the band. Everybody sings, plays, harmonizes, dances, and runs. They change instruments and clothes. Bryne appears in the Big Suit. The backdrop is often black, but sometimes it displays words, images, or children's drawings. The band cooks for 18 songs, the lyrics are clear, the house rocks. In this concert film, the Talking Heads hardly talk, don't stop, and always make sense.

Oakland A's GM Billy Beane is handicapped with the lowest salary constraint in baseball. If he ever wants to win the World Series, Billy must find a competitive advantage. Billy is about to turn baseball on its ear when he uses statistical data to analyze and place value on the players he picks for the team.